Cerebral hypoxia Totally Explained

Everything about Cerebral Hypoxia totally explained

ť For other uses of the term "hypoxia", see hypoxia.

Cerebral hypoxia refers to deprivation of oxygen supply to brain tissue. Mild or moderate cerebral hypoxia is sometimes known as diffuse cerebral hypoxia. It can cause confusion and fainting, but its effects are reversible. Total deprivation of oxygen to the brain is called cerebral anoxia. Extended periods of cerebral hypoxia can lead to brain death or permanent brain damage.
Most cases of cerebral hypoxia are caused by a sudden change in brain oxygen levels. The body can normally respond to mild gradual changes in blood oxygen with little or no noticeable effect on brain function. The acclimatization process used by high altitude climbers is an example of such adjustment.
The presence of cerebral hypoxia symptoms indicates that the brain has been overwhelmed by a change in its oxygen supply. Consequently, even mild symptoms of cerebral hypoxia require immediate medical attention.

Classification

Cerebral hypoxia is typically grouped into four categories depending on the severity and location of the brain’s oxygen deprivation:

Diffuse cerebral hypoxia. A mild to moderate impairment of brain function due to low oxygen levels in the blood.
Focal cerebral ischemia. A small localized reduction in the flow of oxygen from the blood to the brain. Damage to neurons is usually irreversible. Mild strokes.
Cerebral infarction. A complete stoppage of the flow of oxygen from the blood to a region of the brain. Significant irreversible brain damage occurs in the region around the blockage. Major strokes are an example of cerebral infarction.
Global cerebral ischemia. A complete stoppage of blood flow to the brain.

Cerebral hypoxia can also be classified by the cause of the reduced brain oxygen:

Hypoxic hypoxia. Limited oxygen in the environment causes reduced brain function. Divers, aviators, mountain climbers and fire fighters are all at risk for this kind of cerebral hypoxia. The term also includes oxygen deprivation due to obstructions in the lungs. Choking, strangulation, the crushing of the windpipe all cause this sort of hypoxia. Severe asthmatics may also experience symptoms of hypoxic hypoxia.
Hypemic hypoxia. Reduced brain function is caused by inadequate oxygen in the blood despite adequate environmental oxygen. Anemia and carbon monoxide poisoning are common causes of hypemic hypoxia.
Ischemic hypoxia (a.k.a. stagnant hypoxia). Reduced brain oxygen is caused by inadequate blood flow to the brain. Stroke, shock, and heart attacks are common causes of stagnant hypoxia. Ischemic hypoxia can also be created by pressure on the brain. Cerebral edema, brain hemorrhages and hydrocephalus exert pressure on brain tissue and impede their absorption of oxygen.
Histotoxic hypoxia. Oxygen is present in brain tissue but can't be metabolized. Cyanide poisoning is a well known example.

Causes

Cerebral hypoxia can be caused by any event that severely interferes with the brain's ability to receive or process oxygen. This event may be internal or external to the body.
   Mild and moderate forms of cerebral hypoxia may be caused by various diseases that interfere with breathing and blood oxygenation. Severe asthma and various sorts of anemia can cause some degree of diffuse cerebral hypoxia. Other causes include work in nitrogen rich environments, ascent from a deep water dive, flying at high altitudes in an un-pressurized cabin, and intense exercise at high altitudes prior to acclimatization.
   Severe cerebral hypoxia and anoxia is usually caused by traumatic events. Examples include choking, drowning, strangulation, smoke inhalation, drug overdoses, crushing of the trachea, status asthmaticus, and shock.
   It is also recreationally self-induced in the choking game and in autoerotic asphyxiation.

Signs and symptoms

The brain requires approximately 3.3 ml of oxygen per 100 g of brain tissue per minute. Initially the body responds to lowered blood oxygen by redirecting blood to the brain and increasing cerebral blood flow. Blood flow may increase up to twice the normal flow but no more. If the increased blood flow is sufficient to supply the brain’s oxygen needs then no symptoms will result. However, if blood flow can't be increased or if doubled blood flow doesn't correct the problem, symptoms of cerebral hypoxia will begin to appear. Mild symptoms include difficulties with complex learning tasks and reductions in short-term memory. If oxygen deprivation continues, cognitive disturbances and decreased motor control will result.
Objective measurements of the severity of cerebral hypoxia depend on the cause. Blood oxygen saturation may be used for hypoxic hypoxia, but is generally meaningless in other forms of hypoxia. In hypoxic hypoxia 95-100% saturation is considered normal. 91-94% is considered mild. 86-90% is considered moderate. Anything below 86% is considered severe.
It should be noted that cerebral hypoxia refers to oxygen levels in brain tissue, not blood. Blood oxygenation will usually appear normal in cases of hypemic, ischemic and hystoxic cerebral hypoxia. Even in hypoxic hypoxia blood measures are only an approximate guide – the oxygen level in the brain tissue will depend on how the body deals with the reduced oxygen content of the blood.

Treatment

The first goal of treatment is to restore oxygen to the brain. The method of restoration depends on the cause of the hypoxia. For mild to moderate cases of hypoxia, removal of the cause of hypoxia may be sufficient. Inhaled oxygen may also be provided. In severe cases treatment may also involve life support and damage control measures.
   A deep coma will interfere with body’s breathing reflexes even after the initial cause of hypoxia has been dealt with. Mechanical ventilation may be required. Additionally severe cerebral hypoxia causes an elevated heart rate. In extreme cases the heart may tire and stop pumping. CPR, defibrilation, epinephrine, and atropine may all be tried in an effort to get the heart to resume pumping.
   In severe cases it's extremely important to act quickly. Brain cells are very sensitive to reduced oxygen levels. Once deprived of oxygen that'll begin to die off within five minutes.
   If hypoxia results in coma, the length of unconsciousness is often used as an indication of long term damage. In some cases coma can give the brain an opportunity to heal and regenerate, but, in general, the longer a coma continues the greater the likelihood that the person will remain in a vegetative state until death. Families of coma victims often have idealized images of the outcome based on Hollywood movie depictions of coma. Adjusting to the realities of ventilators, feeding tubes, bedsores and muscle wasting may be difficult. Treatment decision often involve complex ethical choices and can strain family dynamics.

Further Information

Get more info on 'Cerebral Hypoxia'.

External Link Exchanges

Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:

<a href="http://cerebral_hypoxia.totallyexplained.com">Cerebral hypoxia Totally Explained</a>

Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned.